Thursday, 20 January 2011

Super resolution microscopy - OMX 3D SIM

Super resolution microscopy, is a powerful new 3D tool that captures cellular processes unfolding at nanometre scales; helps scientists to discover the way, Malaria Parasites, attack Red Blood Cells.

Imaging technology is constantly developing from Simple lens, XRay, to Sophisticated Telescopes.
  • Satellite Images to Nanometre Scales in the molecules.
  • Body Scans at Airports
  • Luggage Scans
  • CT Scans
  • MRI Scans
  • Endoscopy/ Ureteroscopy and similar techniques.
  • Biometrics Scan
  • Iris Scan
  • Narco Analysis (Truth Test with Serum)
  • Brain Alalysis
  • Telescopes (Hubble etc.)
  • (Ultra Sound/ Sonar Signals transmitted thru High Frequency Soungs are its siblings)

Deficiencies of Naked eye are made up with Optical Technology advancements and Brain Functionality Imitating Technology. Great to know the achievements and its utilities to humanity in the removal of afflictions.

But what about the insight, foresight, hindsight and farsightedness?  Though not related with the optical nerve and opthalmological aspect, sight of the mind is the concern here.
  • Lack of insight handicaps several of our functions perennially and perpetually.  And materialistic.
  •  Lack of Empathy, resulting from obliviousness to other's (at least rightful) concerns and expressions.
  • Lack of Hindsight causes the repetitive foolish mistakes.
  • Lack of Farsightedness, results in greedy destruction of values, resources.
(Eyes, pump in information and mind has to analyse it properly and act in accordance. Let us hope our attempts at it)
Scientists claim to have for the first time caught malaria parasites in the act of invading red blood cells, a major breakthrough which could pave the way for developing more effective treatments for the disease. 

An international team, led by Walter and Eliza Hall Institute, has used new image and cell technologies to obtain the images of how malaria parasites attack red blood cells, the 'Cell Host & Microbe' journal reported 

Lead scientist Dr Jake Baum said the real breakthrough for the team had been the ability to capture high-resolution images of the parasite at each and every stage of invasion, and to do so reliably and repeatedly.

It is the first time we've been able to actually visualise this process in all its molecular glory, combining new advances developed at the institute for isolating viable parasites with innovative imaging technologies. 

"Super resolution microscopy has opened up a new realm of understanding into how malaria parasites actually invade the human red blood cell.

"Whilst we have observed this miniature parasite drive its way into the cell before, the beauty of the new imaging technology is that it provides a quantum leap in the amount of detail we can see, revealing key molecular and cellular events required for each stage of the invasion process," Baum said.

The imaging technology, called OMX 3D SIM super resolution microscopy, is a powerful new 3D tool that captures cellular processes unfolding at nanometre scales.

"This is just the beginning of an exciting new era of discoveries enabled by this technology that will lead to a better understanding of how microbes such as malaria, bacteria and viruses cause infectious disease," team member Professor Cynthia Whitchurch said.

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